Guten Morgen.... gähn....
Einfluß von Elektrosmog, Radiowellen , Handys etc... is ne olle Kamelle...
Ich benutze nur im Notfall mal ein Handy:
Effects of electromagnetic field exposure on gene transcription.
Phillips JL.
Pettis Memorial Veterans Administration Medical Center, Loma Linda, California 92357.
Exposure of whole animals, isolated tissues, and cells to electromagnetic fields of various characteristics has resulted in a substantial literature detailing a wide range of effects at the morphological, physiological, biochemical, and molecular levels. In recent years, considerable effort has been devoted to defining a mechanism by which electromagnetic fields can couple to biological systems and generate this plethora of effects. As a consequence, there has been a growing interest in electromagnetic field-induced alterations in gene expression. Key studies are discussed which indicate that exposure of several cell types to electromagnetic fields that differ in waveform, amplitude, and frequency induced general changes in gene transcription. Moreover, exposure of T-lymphoblastoid cells to a 60 Hz sinusoidal magnetic field altered the transcription of genes encoding c-fos, c-jun, c-myc, and protein kinase C. Future studies in this area should focus on independent replication of key studies and identification of which events in the signal transduction pathways leading to gene transcription are altered by electromagnetic field exposure
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Department of Pathology, Columbia University Health Sciences, New York, New York, USA.
Low frequency (< 300 Hz) electromagnetic (EM) fields induce biological changes that include effects ranging from increased enzyme reaction rates to increased transcript levels for specific genes. The induction of stress gene HSP70 expression by exposure to EM fields provides insight into how EM fields interact with cells and tissues. Insights into the mechanism(s) are also provided by examination of the interaction of EM fields with moving charges and their influence on enzyme reaction rates in cell-free systems. Biological studies with in vitro model systems have focused, in general, on the nature of the signal transduction pathways involved in response to EM fields. It is likely, however, that EM fields also interact directly with electrons in DNA to stimulate biosynthesis. Identification of an EM field-sensitive DNA sequence in the heat shock 70 (HSP70) promoter, points to the application of EM fields in two biomedical applications: cytoprotection and gene therapy. EM field induction of the numerous epidemiological studies have linked exposure to low-energy EM fields to increased cancer risk.stress protein hsp70 may also provide a useful biomarker for establishing a science-based safety standard for the design of cell phones and their transmission towers. Copyright 2002 Wiley-Liss, Inc.
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Do electromagnetic fields interact directly with DNA?
Blank M, Goodman R.
Department of Physiology, Columbia University, New York, NY 10032, USA.
The mechanisms whereby electromagnetic (EM) fields stimulate changes in biosynthesis in cells are not known. It has has generally been assumed that EM fields first interact with cell membranes, but this pathway may not be only one. Interactions with membranes are well documented, but recent studies of EM signal transduction in the membrane Na,K-ATPase are best explained by direct interaction of electric and magnetic fields with mobile charges within the enzyme. Interaction with moving charges may be a mechanism that is operative in other biopolymers. Recent studies on DNA have shown that large electron flows are possible within the stacked base pairs of the double helix. Therefore, gene activation by magnetic fields could be due to direct interaction with moving electrons within DNA. Electric fields as well as magnetic fields stimulate transcription, and both fields could interact with DNA directly. The mechanism of EM field-stimulated transcription may be related to the process in striated muscles, where endogenous electrical activity induces the synthesis of new proteins.
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The effects of low-energy 60-Hz environmental electromagnetic fields upon the growth-related enzyme ornithine decarboxylase.
Byus CV, Pieper SE, Adey WR.
Division of Biomedical Sciences, University of California, Riverside 92521.
People living in the industrial society of today are unavoidably exposed to low-energy electromagnetic (EM) radiation. The potential risk to human health of such exposure has received much study. In this regard, numerous epidemiological studies have linked exposure to low-energy EM fields to increased cancer risk. We investigated the ability of low-energy 60-Hz EM fields to alter the activity of ornithine decarboxylase (ODC) in a number of established cell lines. The activity of ODC, the controlling enzyme in polyamine biosynthesis, has been shown to be elevated in growing cells or tissues and during the process of tumor promotion. A 1-h exposure to a 60-Hz EM field of an intensity of 10 mV/cm produced a 5-fold increase in ODC activity in human lymphoma CEM cells and a 2- to 3-fold increase in mouse myeloma cells (P3) relative to the unexposed cultures. Depending upon the cell type, ODC activity increased during the 1-h exposure period and remained elevated for several hours after the field exposure ended. In another series of experiments, fields of an intensity as low as 0.1 mV/cm for a 1-h period produced a 30% increase in the activity of ODC in Reuber H35 hepatoma cells grown in monolayer culture. In the H35 cells, continuous exposure to the 60-Hz EM field (10 mV/cm) for periods of 2 and 3 h resulted in either no increase in ODC activity (2 h) or a decrease in enzyme activity (3 h) compared to the unexposed control cultures. The data is discussed in relation to possible molecular mechanisms of field-cell interaction, the importance of the exposure intervals altering cellular ODC activity and the potential ability of 60-Hz EM fields to serve as a tumor promoting stimulus.
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Cellular telephones and effects on the brain: the head as an antenna and brain tissue as a radio receiver.
Weinberger Z, Richter ED.
Jerusalem College of Technology, Jerusalem, Israel.
Headache and other neuropsychological symptoms occur in users of cellular telephones, and controversy exists concerning risks for brain cancer. We hypothesize these effects result from the head serving as an antenna and brain tissue as a radio receiver. The frequencies for transmission and reception by cellular telephones, about 900 MHz for analog and 1800 MHz for digital transmission, have wavelengths of 33-35 and 16-17 cm, respectively. Human heads are oval in shape with a short axis about 16 to 17 cm in length. Near the ear there will be a cross-section in the head with an axis half the wavelength of RF/MW transmissions of 900 MHz and equal to the wavelength of RF/MW transmissions at 1800 MHz. Therefore, the human head can serve as a lossy resonator for the electromagnetic radiation emitted by the cellular telephone, absorbing much of the energy specifically from these wavelengths. Brain cells and tissues demodulate the cell-phone's audio frequencies from the radio frequency carrier. Low audio frequencies in the ranges of alpha and beta waves affect these waves and thereby influence brain function. These effects state the case for a precautionary policy. Copyright 2002 Elsevier Science Ltd.
FAZIT für die , die das nicht lesen können: Es ist bewiesen, das electromagnetische Felder schädlich sind.
Tschüß,
Philipp
